Shock Clinical Challenges

Overview

Shock Epidemiology is a life-threatening failure of adequate oxygen delivery to the tissues leading to inadequate blood oxygen saturation. Challenges remain in the current treatment of shock patients [1][2].

Current limitations in treatment of shock patients

Shunt Index

Current non-invasive cardiac output monitors do not measure shunt, so true cardiac output measurements are not yet achieved.

Ventilator Settings

Incorrect ventilator settings may induce lung damage, worsening outcomes.

Invasive

Currently, there is no non-invasive monitoring technique to assess shunt fraction.

Shock remains a problem globally

15M

Shock affects more than 15 million patients globally [2]

40%

Mortality rates for shock are between 40-60% [2]

30%

COVID-19 patients admitted to ICU resulted in Shock [3].

— learn about how we address Shock challenges

1. Medicine, S.o.C.C. Critical Care Statistics. Available from: https://www.sccm.org/Communications/Critical-Care-Statistics

2. Fleischmann, C., et al., Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations. American Journal of Respiratory and Critical Care Medicine, 2016. 193(3): p. 259-272.

3. Phua, J., et al., Asian Critical Care Clinical Trials Group. (2020). Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. The Lancet Respiratory Medicine, 8(5), 506-517